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dctS [2017-8-11 16:0:3]
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dctS [2017-8-11 16:0:3]

two-component sensor kinase, regulation of the dctS-dctR-dctP operon
Locus
BSU04450
Isoelectric point
6.20
Molecular weight
59.77 kDa
Protein length
535 aa Sequence Blast
Gene length
1605 bp Sequence Blast
Function
regulation of the dctS-dctR-dctP operon
Product
two-component sensor kinase
Essential
no
Synonyms
ydbF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of organic acids
  • Information processing → Protein synthesis, modification and degradation → Protein modification → Protein kinases
  • Information processing → Regulation of gene expression → Transcription factors and their control → Control of two-component response regulators → Two-component sensor kinase
  • Groups of genes → Membrane proteins
  • Groups of genes → Phosphoproteins → Phosphorylation on a His residue

    • Gene

    Coordinates
    497,768 → 499,375

    The protein

    Catalyzed reaction/ biological activity

  • autophosphorylation, phosphorylation of DctR

    • Domains

  • two transmembrane segments
  • PAS domain
  • C-terminal histidine phosphotransferase domain

    • Modification

  • autophosphorylation on a His residue

    • Effectors of protein activity

  • DctB and DctP act as co-sensors with DctS PubMed

    • Localization

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    dctS-dctR-dctP
    Description
    PubMed

    Regulation

  • part of the iron sparing response, strong down-regulation in a fur mutant (Fur, FsrA) PubMed
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    Biological materials

    Mutant

  • GP225 (dctS::cat), available in Jörg Stülke's lab

    • References

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